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A comparison of the treatment outcomes of cerebral gas embolism at 2.8 ATA in comparison with 6 ATA New!

Author names and affiliations: Bin Zhang1Hongjie Yi1Yue Jiang1Chenggang Zheng

Department of Hyperbaric Oxygen, Changhai Hospital, Naval Medical University, 168 Changhai Rd, Shanghai, 200433, China.

The authors contributed equally to this work.

 

Objective: To investigate the effect of 6 ATA air/ oxygen treatment schemes and 2.8 ATA oxygen inhalation schemes on cerebral gas embolism. 

Methods: 29 patients with cerebral gas embolisms admitted from January 2014 to June 2022 were retrospectively included. The patients were divided into 6 ATA air/ oxygen treatment scheme groups (14 cases) and 2.8 ATA oxygen inhalation therapy scheme groups (15 cases). The Glasgow Coma Scale (GCS) was used to evaluate the therapeutic effect before and after treatment. The effective standard of treatment was the recovery of consciousness (a GCS score>8). 

Results: There was no significant difference between the two groups regarding gender, age, cause of disease, time of onset, and GCS score before treatment (P>0.05). The two groups had no significant difference regarding GCS scores after one day and one week of treatment (P>0.05). After one week of treatment, 78.6% (11 of 14) of patients in the 6 ATA group and 80.0% (12 of 15) in the 2.8 ATA group improved by reaching primary end point of GCS >8. 

Conclusion: The 2.8 ATA oxygen inhalation scheme can effectively treat cerebral gas embolism, and its effect is similar to the 6 ATA air/ oxygen treatment scheme.