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From the 2025 2nd Quarter Pressure

Elaine M. Silverman, MD, MPH
Linda Zhang, MS
Jay C. Buckey, MD

Multicenter Registry Update

This update highlights cases where hyperbaric oxygen treatment was used for Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL). The Registry has accumulated a substantial number of cases, and we are beginning a comprehensive data analysis.

Here is just a brief overview:

  • Total number of cases entered = 556; 256 with complete pre-and post-treatment pure tone average data
  • Mean improvement in Pure-Tone Average (PTA) was 14 dB (p<0.0001)
  • The mean percentage of Word Recognition improved significantly
  • Mean Quality of Life measures increased moderately
  • Patient satisfaction with treatment was generally positive, but long-term follow-up results will require more in-depth analysis.

Graphs corresponding to the above bullet points follow below.

Although ISSNHL is a UHMS-approved indication for Hyperbaric Oxygen Treatment, access to hyperbaric facilities varies, and referral patterns seem to reflect different levels of acceptance of HBO2 as a potentially beneficial treatment. Analysis and publication of registry data is a valuable tool for educating us and establishing stronger treatment guidelines and recommendations.

If you plan to attend the 2025 AsMA-UHMS Joint Annual Scientific Meeting in Atlanta and would like to learn more about the Multicenter Registry for Hyperbaric Oxygen Treatment, please look for our Registry review poster (B14) and come by to chat!

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